Hey, I just ran into Penny.
She seemed UPSET about something.
The Big Bang Theory Season 1, Episode 4
...and I'm UPSET about something
with Leonard.
The Big Bang Theory Season 3, Episode 2
She'll get UPSET and honestly,
I'm a little terrified of her.
The Big Bang Theory Season 8, Episode 1
Okay, I know you're UPSET
The Big Bang Theory Season 7, Episode 24
Sheldon, I know you're UPSET
about the paper, okay.
The Big Bang Theory Season 12, Episode 10